IDA is a common comorbidity in patients with GI or liver disorders. In general, the origin of IDA can be multifactorial, with bleeding, malabsorption and inflammation playing important roles in the context of different GI conditions. IDA can contribute substantially to the morbidity and mortality of the underlying disorder and even ID without anemia can reduce quality of life, exercise capacity and cognitive function. Therefore, effective treatment of ID and IDA as well as prevention of recurrence are necessary and may provide an important alleviation of the overall disease burden.
The standard laboratory approach used to investigate IDA would benefit from inclusion of TSAT assessment, which is less affected by inflammatory reactions than the commonly-used acute-phase protein serum ferritin. Oral iron, often selected as the initial treatment option, has considerable limitations in GI patients due to severe GI side effects, inadequate absorption and a slow course of action. Furthermore, patient compliance with oral iron therapy is often poor.
Case study- Iron deficiency anemia
If oral therapy fails or is inadvisable, intravenous iron replacement is a valuable option. Intravenous iron therapy is more efficient than oral iron, and faster at increasing Hb levels and replenishing iron stores. Iron therapy should be continued until iron stores are completely replenished. Advanced Search. This Article.
Academic Rules and Norms of This Article. Citation of this article. Anemia and iron deficiency in gastrointestinal and liver conditions.
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- Anemia and iron deficiency in gastrointestinal and liver conditions.
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Corresponding Author of This Article. Publishing Process of This Article. Research Domain of This Article. Gastroenterology and Hepatology. Article-Type of This Article. Open-Access Policy of This Article.
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. Number of Hits and Downloads for This Article. Total Article Views All Articles published online. Times Cited of This Article. Journal Information of This Article. Published by Baishideng Publishing Group Inc.
All rights reserved. World J Gastroenterol. Author contributions : All authors contributed equally to the literature search and data interpretation; Stein J prepared the draft manuscript; all authors reviewed and approved the manuscript prior to submission. Conflict-of-interest statement : No potential conflicts of interest relevant to this article were reported. Open-Access : This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. Key Words: Iron deficiency anemia , Gastrointestinal bleeding , Nonsteroidal anti-inflammatory drugs , Gastritis , Infection , Bariatric surgery , Celiac disease , Gastrointestinal neoplasm , Chronic hepatitis , Non-alcoholic fatty liver disease.
NSAID-associated fecal blood loss. Portal hypertensive gastropathy and gastric antral vascular ectasia. Intestinal parasitic infections. Chronic hepatitis and liver conditions. Non-alcoholic fatty liver disease.
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Iron deficiency in the elderly population, revisited in the hepcidin era. Front Pharmacol. Anemia of gastrointestinal origin in the elderly. Pract Gastroenterol. Use of whole gut perfusion to investigate gastrointestinal blood loss in patients with iron deficiency anaemia. Curr Treat Options Gastroenterol. An etiologic profile of anemia in geriatric patients. Intravenous iron in digestive diseases: a clinical re view.
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